G-CSF after myocardial infarction accelerates angiogenesis and reduces fibrosis in swine.

@article{Sato2008GCSFAM,
  title={G-CSF after myocardial infarction accelerates angiogenesis and reduces fibrosis in swine.},
  author={Takatoshi Sato and Hidekazu Suzuki and Taro Kusuyama and Yasutoshi Omori and Teruko Soda and Fumiyoshi Tsunoda and Makoto Shoji and Yoshitaka Iso and Shinji Koba and Eiichi Geshi and Takashi Katagiri and Keisuke Kawachi and Kohei Wakabayashi and Youichi Takeyama},
  journal={International journal of cardiology},
  year={2008},
  volume={127 2},
  pages={166-73}
}
OBJECTIVE Recent studies have suggested that granulocyte colony-stimulating factor (G-CSF) may improve cardiac function after acute myocardial infarction (AMI) by accelerating angiogenesis or cardiomyogenesis, but negative results and side effect of G-CSF have also been reported. However, no previous studies have used large animal models of ischemia/reperfusion to investigate the effect and side effect of G-CSF after AMI. METHODS The diagonal branch of the left anterior descending coronary… CONTINUE READING

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