G 1 Cell Cycle Arrest and Apoptosis Are Induced in NIH 3 T 3 Cells by KN - 93 , an Inhibitor of CaMK - lI ( the Multifunctional Ca 2 / CaM Kinase ) 1

Abstract

Abstrad CaMK-II (the type II multifundional Ca2’/calmodulin kinase) is a ubiquitous serine/threonine protein kinase that is adivated by Ca2 and calmodulin (CaM) and has been implicated in cell cycle control. NIH 3T3 fibroblast cytosolic extrads contain CaMK-lI enzymatic adivity and two major Ca2 /CaM-dependent phosphoproteins of Mr 55,000 and 1 1 5,000… (More)

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@inproceedings{Kinase2007G1C, title={G 1 Cell Cycle Arrest and Apoptosis Are Induced in NIH 3 T 3 Cells by KN - 93 , an Inhibitor of CaMK - lI ( the Multifunctional Ca 2 / CaM Kinase ) 1}, author={CaM Kinase and Robert M. Tombes and Steven Grant and Eric H. Westin and Geoffrey W. Krystal}, year={2007} }