Gβγ-Mediated Regulation of Golgi Organization Is through the Direct Activation of Protein Kinase D

@article{Jamora1999GMediatedRO,
  title={Gβγ-Mediated Regulation of Golgi Organization Is through the Direct Activation of Protein Kinase D},
  author={Colin Jamora and Norma Yamanouye and J. H. van Lint and John Laudenslager and Jackie R. Vandenheede and D J Faulkner and Vivek Malhotra},
  journal={Cell},
  year={1999},
  volume={98},
  pages={59-68}
}
IQ and G␤␥ is inhibited by the inclusion of G␣-GDP, which prevents the interaction of G␤␥ with its down-* Biology Department † Scripps Institution of Oceanography stream target(s) by sequestering these subunits into an inactive heterotrimeric complex (Jamora et al., 1997). We have found that G␤␥ is capable of fragmenting Golgi membranes in permeabilized cells that have been ‡ Department of Cancer Biology The Salk Institute washed with 1 M KCl to remove cytosolic and loosely attached peripheral… CONTINUE READING