Fyn kinase is involved in cleavage furrow ingression during meiosis and mitosis.

@article{Levi2010FynKI,
  title={Fyn kinase is involved in cleavage furrow ingression during meiosis and mitosis.},
  author={Mattan Levi and B. Maro and Ruth Shalgi},
  journal={Reproduction},
  year={2010},
  volume={140 6},
  pages={827-34}
}
Fertilization of mammalian oocytes triggers their exit from the second meiotic division metaphase arrest. The extrusion of the second polar body (PBII) that marks the completion of meiosis is followed by the first mitotic cleavage of the zygote. Several lines of evidence in somatic cells imply the involvement of Fyn, an Src family kinase (SFK), in cell cycle control and actin functions. In this study, we demonstrate, using live cell confocal imaging and microinjection of Fyn cRNAs, the… CONTINUE READING

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