Fyn deficiency attenuates renal fibrosis by inhibition of phospho-STAT3.


The hallmark of renal tubulointerstitial fibrosis is the accumulation of myofibroblasts and extracellular matrix proteins. Fyn, a member of the Src family of kinases, has diverse biological functions including regulation of mitogenic signaling and proliferation and integrin-mediated interaction. Src family proteins promote pulmonary fibrosis by augmenting… (More)
DOI: 10.1016/j.kint.2016.06.038


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