Future target-based drug discovery for tuberculosis?

@article{Kana2014FutureTD,
  title={Future target-based drug discovery for tuberculosis?},
  author={B. Kana and P. Karakousis and T. Parish and T. Dick},
  journal={Tuberculosis},
  year={2014},
  volume={94 6},
  pages={
          551-6
        }
}
New drugs that retain potency against multidrug/extensively drug-resistant strains of Mycobacterium tuberculosis, with the additional benefit of a shortened treatment duration and ease of administration, are urgently needed by tuberculosis (TB) control programs. Efforts to develop this new generation of treatment interventions have been plagued with numerous problems, the most significant being our insufficient understanding of mycobacterial metabolism during disease. This, combined with… Expand
Mycobacterial drug discovery
Early Drug Development and Evaluation of Putative Antitubercular Compounds in the -Omics Era
Pyridine and quinoline molecules as crucial protagonists in the never-stopping discovery of new agents against tuberculosis.
Tuberculosis Drug Discovery: A Decade of Hit Assessment for Defined Targets
Emerging Approaches to Tuberculosis Drug Development: At Home in the Metabolome.
...
1
2
3
4
...

References

SHOWING 1-10 OF 56 REFERENCES
Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases
TMC207 becomes bedaquiline, a new anti-TB drug.
Sustainable tuberculosis drug development.
  • R. Wallis
  • Medicine
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2013
How antibacterials really work: impact on drug discovery.
PA-824, moxifloxacin and pyrazinamide combination therapy for tuberculosis
...
1
2
3
4
5
...