Future prospects for tissue engineered lung transplantation: decellularization and recellularization-based whole lung regeneration.

@article{Tsuchiya2014FuturePF,
  title={Future prospects for tissue engineered lung transplantation: decellularization and recellularization-based whole lung regeneration.},
  author={Tomoshi Tsuchiya and Amogh Sivarapatna and Kevin A. Rocco and Atsushi Nanashima and Takeshi Nagayasu and Laura E. Niklason},
  journal={Organogenesis},
  year={2014},
  volume={10 2},
  pages={196-207}
}
The shortage of donor lungs for transplantation causes a significant number of patient deaths. The availability of laboratory engineered, functional organs would be a major advance in meeting the demand for organs for transplantation. The accumulation of information on biological scaffolds and an increased understanding of stem/progenitor cell behavior has led to the idea of generating transplantable organs by decellularizing an organ and recellularizing using appropriate cells. Recellularized… CONTINUE READING
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