Future direction in pharmacotherapy for non-neurogenic male lower urinary tract symptoms.

@article{Soler2013FutureDI,
  title={Future direction in pharmacotherapy for non-neurogenic male lower urinary tract symptoms.},
  author={Roberto Soler and Karl-Erik Andersson and Michael B Chancellor and Christopher R Chapple and William Chet de Groat and Marcus J Drake and Christian Gratzke and Richard Lee and Francisco I. S. Cruz},
  journal={European urology},
  year={2013},
  volume={64 4},
  pages={610-21}
}
BACKGROUND The pathophysiology of male lower urinary tract symptoms (LUTS) is highly complex and multifactorial. The shift in perception that LUTS are not sex or organ specific has not been followed by significant innovations regarding the available drug classes. OBJECTIVE To review pathophysiologic mechanisms and clinical and experimental data related to the development of new pharmacologic treatments for male LUTS. EVIDENCE ACQUISITION The PubMed database was used to identify articles… CONTINUE READING