Future Treatment Options in PBC.

  title={Future Treatment Options in PBC.},
  author={John Moore Vierling},
  journal={Seminars in liver disease},
  volume={25 3},
Because the etiopathogenesis of PBC is incompletely defined, curative therapies have not been identified, and the focus has been on prevention of disease progression. Ursodeoxycholic acid retards progression and is likely to be combined with newer therapies in future trials. Advances in our understanding of the roles of retroviral infection and autoimmune responses of T and B cells to PBC-specific autoantigens provides rationales for studies of the safety and efficacy of antiretroviral… CONTINUE READING

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