Futility sustains memory T cells.


Memory T cells display a distinct metabolic profile compared to effector T cells. In this issue of Immunity, O'Sullivan et al. (2014) report that memory T cells activate a "futile cycle" of de novo fatty-acid synthesis and concurrent fatty-acid oxidation to generate ATP for cell survival.

DOI: 10.1016/j.immuni.2014.06.009

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@article{Weinberg2014FutilitySM, title={Futility sustains memory T cells.}, author={Samuel E. Weinberg and Navdeep S Chandel}, journal={Immunity}, year={2014}, volume={41 1}, pages={1-3} }