Fusion protein linkers: property, design and functionality.

  title={Fusion protein linkers: property, design and functionality.},
  author={Xiaoying Chen and Jennica L Zaro and W C Shen},
  journal={Advanced drug delivery reviews},
  volume={65 10},
As an indispensable component of recombinant fusion proteins, linkers have shown increasing importance in the construction of stable, bioactive fusion proteins. This review covers the current knowledge of fusion protein linkers and summarizes examples for their design and application. The general properties of linkers derived from naturally-occurring multi-domain proteins can be considered as the foundation in linker design. Empirical linkers designed by researchers are generally classified… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 7 times. VIEW TWEETS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 143 extracted citations

A review on chimeric xylanases: methods and conditions

3 Biotech • 2017
View 4 Excerpts
Highly Influenced

The promises and challenges of fusion constructs in protein biochemistry and enzymology

Applied Microbiology and Biotechnology • 2016
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…