Fusion-mediated microinjection of active amine and diamine oxidases into cultured cells: effect on protein and DNA synthesis in chick embryo fibroblasts and in glioma cells.

@article{Bachrach1987FusionmediatedMO,
  title={Fusion-mediated microinjection of active amine and diamine oxidases into cultured cells: effect on protein and DNA synthesis in chick embryo fibroblasts and in glioma cells.},
  author={Uriel Bachrach and I Ash and Lutfi Abu-Elheiga and Maty Hershkovitz and Abraham Loyter},
  journal={Journal of cellular physiology},
  year={1987},
  volume={131 1},
  pages={92-8}
}
Serum amine oxidase and/or porcine kidney diamine oxidase were trapped within reconstituted Sendai virus envelopes, and retained their activity. The trapped enzymes that were detected by radioimmunoblots were microinjected into cultured cells by fusion. When diamine oxidase was microinjected into cultured fibroblasts of chick or rat embryos, a temporary arrest in protein and DNA synthesis was observed. The inhibitory effect was more significant when both serum amine oxidase and kidney diamine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Some new functions of amine oxidases

InflammoPharmacology • 2003
View 1 Excerpt

Similar Papers

Loading similar papers…