Fusion between myoblasts and adult muscle fibers promotes remodeling of fibers into myotubes in vitro.

Muscle satellite cells are residual embryonic myoblast precursors responsible for muscle growth and regeneration. In order to examine the role of satellite cells in the initial events of muscle regeneration, we placed individual mature rat muscle fibers in vitro along with their satellite cells. When the satellite cells were allowed to proliferate, they… CONTINUE READING