Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells

@inproceedings{Kemp2011FusionBH,
  title={Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells},
  author={Kevin M Kemp and David E Gordon and David Cameron Wraith and Elizabeth A Mallam and Elizabeth M. Hartfield and James. B. Uney and Alastair Wilkins and Neil J. Scolding},
  booktitle={Neuropathology and applied neurobiology},
  year={2011}
}
AIMS we explored whether cellular fusion and heterokaryon formation between human and rodent cells in the cerebellum of mice occurs after intravenous injection of human bone marrow-derived mesenchymal stem cells (MSCs). The influence of central nervous system inflammation on this process was also assessed. In addition, we examined whether tumour necrosis factor (TNF)-alpha and interferon (IFN)-gamma, factors associated with inflammation, increase cellular fusion between human MSCs and rodent… CONTINUE READING

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