Fusaproliferin production by Fusarium subglutinans and its toxicity to Artemia salina, SF-9 insect cells, and IARC/LCL 171 human B lymphocytes.

@article{Logrieco1996FusaproliferinPB,
  title={Fusaproliferin production by Fusarium subglutinans and its toxicity to Artemia salina, SF-9 insect cells, and IARC/LCL 171 human B lymphocytes.},
  author={Antonio Francesco Logrieco and Antonio Moretti and Francesca Fornelli and Vincenzo Fogliano and Alberto Ritieni and Maria Filomena Caiaffa and Giacomino Randazzo and Antonio Bottalico and Luigi Macchia},
  journal={Applied and environmental microbiology},
  year={1996},
  volume={62 9},
  pages={3378-84}
}
Fusarium subglutinans is an important pathogen of maize and other commodities worldwide. We examined MRC-115 and 71 other F. subglutinans strains from various geographic areas for their ability to synthesize fusaproliferin, a novel toxic sesterterpene recently isolated from F. proliferatum. Fusaproliferin production ranged from 30 to 1,500 micrograms/g of dried ground substrate, with 33 strains producing more than 500 micrograms/g. In particular, strain MRC-115 produced as much as 1,100 to 1… CONTINUE READING

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