Further studies on the early protective responses of pigs following immunisation with high potency foot and mouth disease vaccine.

@article{Barnett2002FurtherSO,
  title={Further studies on the early protective responses of pigs following immunisation with high potency foot and mouth disease vaccine.},
  author={Paul V. Barnett and Sarah J. Cox and Neeraj Aggarwal and Heidi Gerber and Kenneth C McCullough},
  journal={Vaccine},
  year={2002},
  volume={20 25-26},
  pages={3197-208}
}
The ability of an emergency oil adjuvanted foot-and-mouth disease (FMD) vaccine to elicit early protective immunity in pigs against direct contact homologous challenge was examined. All vaccinates showed reduced viraemia and shedding of FMDV, and certain animals were protected, showing no clinical signs. IL-6, IL-8 and IL-12 were consistently detected in challenged animals that had been vaccinated. Other cytokines--IL-1, IL-2, TNF, TGF and interferons--were not detected. This demonstrates that… CONTINUE READING

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