Further studies on the composition and structure of a fucoidan preparation from the brown alga Saccharina latissima.

@article{Bilan2010FurtherSO,
  title={Further studies on the composition and structure of a fucoidan preparation from the brown alga Saccharina latissima.},
  author={Maria I. Bilan and Alexey A. Grachev and Alexander S. Shashkov and Maeve S. Kelly and Craig J. Sanderson and Nikolay E. Nifantiev and Anatolii I. Usov},
  journal={Carbohydrate research},
  year={2010},
  volume={345 14},
  pages={
          2038-47
        }
}
The polysaccharide composition of a fucoidan preparation isolated from the brown alga Saccharina latissima (formerly Laminaria saccharina) was reinvestigated. The preparation was fractionated by anion-exchange chromatography, and the fractions obtained were analyzed by chemical methods combined with NMR spectroscopy. Several 2D procedures, including HSQC, HMQC-TOCSY, and HMQC-NOESY, were used to obtain reliable structural information from the complex spectra, and the signal assignments were… Expand
Preliminary investigation of a highly sulfated galactofucan fraction isolated from the brown alga Sargassum polycystum.
TLDR
The distribution of galactose residues along the polysaccharide backbone seems to be not strictly regular, but the definitive sequence of monomers in the polymeric molecules awaits additional investigation. Expand
Further studies on structure of fucoidan from brown alga Saccharina gurjanovae.
TLDR
Structural simplification of SgF by lowering its molecular weight, desulfation at C-2 and removing of galactose residues by autohydrolysis at 25°C did not decrease its anticancer activity, and this procedure allows obtaining standardized products which can be used as medical. Expand
A sulfated galactofucan from the brown alga Hormophysa cuneiformis (Fucales, Sargassaceae).
TLDR
F3 acts as anticoagulant and is about half as active as the standard low-molecular mass heparin (enoxaparin). Expand
Isolation and structural characterization of fucoidans from the brown algae Fucus vesiculosus
Brown seaweeds are part of a group of organisms that has been used for food, agricultural, pharmaceutical, cosmetic or bioenergy applications. They contain bioactive compounds, namely,Expand
Polysaccharides of algae 68. Sulfated polysaccharides from the Kamchatka brown alga Laminaria bongardiana
Several fucoidan fractions were isolated from the biomass of the Kamchatka brown alga Laminaria bongardiana by hot water extraction followed by anion-exchange chromatography. Fucoidans were found toExpand
Sulfated polysaccharides of the Vietnamese brown alga Sargassum aquifolium (Fucales, Sargassaceae).
TLDR
Fractions of FSA possess anticoagulant, cytotoxic, and antitumor activities, which increase with the degree of sulfation, and three structurally different polysaccharides were identified. Expand
Ion-exchange purification and structural characterization of five sulfated fucoidans from brown algae
TLDR
Ion-exchange chromatography efficiently removes the polysaccharides alginate and laminarin and other contaminants such as proteins and phlorotannins across a broad range of fucoidans from major brown algal orders including Ectocarpales, Laminariales and Fucales. Expand
Chemical composition diversity of fucoidans isolated from three tropical brown seaweeds (Phaeophyceae) species
Abstract. Lutfia FN, Isnansetyo A, Susudarti RA, Nursid M. 2020. Chemical composition diversity of fucoidans isolated from three tropical brown seaweeds (Phaeophyceae) species. Biodiversitas 21:Expand
Structural elucidation of fucoidan from Cladosiphon okamuranus (Okinawa mozuku).
TLDR
The objective of this study was to elucidate the chemical structure of fucoidan from Cladosiphon okamuranus harvested in Japan, and revealed that fucopyranoside units along the backbone are linked, through α-1,3-glycosidic bonds, with fucose branching at C-2, and one sulphate group atC-4 per every three fucOSE units. Expand
Structure of a sulfated xylofucan from the brown alga Punctaria plantaginea.
TLDR
Thepolysaccharide isolated from the brown alga Punctaria plantaginea is a new representative of a complex 'fucoidan' family of sulfated polysaccharides of brown seaweeds. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 25 REFERENCES
A study of fucoidan from the brown seaweed Chorda filum.
TLDR
Other fucoidan fractions from C. filum have more complex carbohydrate composition and give rather complex methylation patterns, which correspond to a quasiregular polysaccharide structure with a branched hexasaccharide repeating unit. Expand
Structural investigation of a fucoidan containing a fucose-free core from the brown seaweed, Hizikia fusiforme.
TLDR
A fucoidan, obtained from the hot-water extract of the brown seaweed, Hizikia fusiforme, was separated into five fractions and showed that the sugar composition was mainly fucose, galactose, mannose, xylose and glucuronic acid. Expand
Structure and pharmacological activities of a sulfated xylofucoglucuronan from the alga Spatoglossum schröederi
TLDR
The xylofucoglucuronan has low anticoagulant and no hemorrhagic activity but, as heparin, has a high activity in stimulating the synthesis of an antithrombotic heparan sulfate from vascular endothelial cells in culture. Expand
Structure of a highly pyruvylated galactan sulfate from the Pacific green alga Codium yezoense (Bryopsidales, Chlorophyta).
A polysaccharide fraction consisting of d-galactose, sulfate, and pyruvate in a molar proportion of 4:2:1 was isolated from the green seaweed Codium yezoense by water extraction followed byExpand
Structure of a fucoidan from the brown seaweed Fucus evanescens C.Ag.
A fucoidan consisting of L-fucose, sulfate and acetate in a molar proportion of 1:1.23:0.36 was isolated from the Pacific brown seaweed Fucus evanescens. The structures of its desulfated andExpand
A sulfated glucuronofucan containing both fucofuranose and fucopyranose residues from the brown alga Chordaria flagelliformis.
TLDR
The fucoidan was shown to contain a backbone of 3-linked alpha-l-fucopyranose residues, about one-third of which are glycosylated at C-2 by alpha-d-glUCopyranosyluronic acid residues. Expand
Marine Bacterial Sulfated Fucoglucuronomannan (SFGM) Lyase Digests Brown Algal SFGM into Trisaccharides
TLDR
Three kinds of trisaccharides were prepared by digesting fucoidan from the brown alga Kjellmaniella crassifolia, with the extracellular enzymes of the marine bacterium Fucobacter marina and tentatively named as sulfated fucoglucuronomannan (SFGM) and SFGM lyase, respectively. Expand
Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies.
TLDR
Fractionation with the cationic detergent cetrimide has allowed achieving a better separation of the galactofucan and uronofucoidan components, which show a high inhibitory activity against herpes simplex virus 1 and 2, with no cytotoxicity. Expand
Structure of a glycoglucuronomannan from the low-viscosity gum of Vochysia lehmannii
The polysaccharide (VSP) from the gum exudate of quaruba (Vochysia lehmannii) had two components of almost identical Mw centred at 24,800, as shown by HSPEC-MALLS. The presence of aggregates wasExpand
A high-viscosity glycoglucuronomannan from the gum exudate of Vochysia thyrsoidea: Comparison with those of other Vochysia spp.
Abstract The polysaccharide (VTh) extracted with water from the gum exudate of the trunk Vochysia thyrsoidea gave a solution of high viscosity and was homogeneous, with M w 92.5 × 10 3 and d n /d c Expand
...
1
2
3
...