Further studies on collagen mRNA: Partial chemical characterization and polyadenylic acid sequence

Abstract

Collagen mRNA has already been purified and characterized by us. Its purity has now been enhanced by two different methods. Gel electrophoresis shows in either method, a single peak with the same mobility already reported: 1.05×106 daltons. Base composition analyses of collagen mRNA purified by either method were almost identical. Chemical analyses of the isolated polyadenylic acid stretch show that it is, 0.48×105 daltons-long, (about 140 nucleotides-long), contains 75% AMP, and is located at the 3′ end of the polymer.

DOI: 10.1007/BF00356941

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Cite this paper

@article{Salles1976FurtherSO, title={Further studies on collagen mRNA: Partial chemical characterization and polyadenylic acid sequence}, author={Jos{\'e} Maria Porcaro Salles and Shigueko Sonohara and Ricardo Renzo Brentani}, journal={Molecular Biology Reports}, year={1976}, volume={2}, pages={517-523} }