Further similarities between cutaneous scarring in the female, red Duroc pig and human hypertrophic scarring.

@article{Zhu2004FurtherSB,
  title={Further similarities between cutaneous scarring in the female, red Duroc pig and human hypertrophic scarring.},
  author={Kathy Q. Zhu and Loren H. Engrav and Richard N. Tamura and Jana A Cole and Pornprom Muangman and Gretchen J. Carrougher and Nicole S. Gibran},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2004},
  volume={30 6},
  pages={
          518-30
        }
}
Knowledge of the pathophysiology of hypertrophic scarring following deep dermal injuries is minimal due to the lack of an animal model. We previously confirmed that thick scars in female, red Duroc pigs (FRDP) are similar to human hypertrophic scar. The purpose of this study was to evaluate TGFbeta1, IGF-1, decorin, and versican expression in FRDP wounds. Deep and shallow wounds on the backs of two FRDPs were studied over 5 months. Immunohistochemistry was performed for TGFbeta1, IGF-1, decorin… CONTINUE READING

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