Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

  title={Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.},
  author={Rachel A. Myers and Blanca E. Himes and Christopher R Gignoux and James J. Yang and William James Gauderman and Cristina Rebordosa and Jianming Xie and Dara G. Torgerson and Albert M. Levin and James W. Baurley and Penelope E. Graves and Rasika A. Mathias and Isabelle Romieu and Lindsey A. Roth and David Conti and Lydiana Avila and Celeste Eng and H. Vora and Michael A Lenoir and Manuel E. Soto-Quiros and Jinghua Liu and Juan C Celed{\'o}n and Joshua M Galanter and Harold J. Farber and Rajesh Kumar and Pedro C. Avila and Kelley E. Meade and D. Serebrisky and Shannon M. Thyne and William Rodriguez-Cintron and Jose Rodriguez-Santana and Luisa N Borrell and Robert F. Lemanske and Eugene Bleecker and Deborah A. Meyers and Stephanie J London and Kathleen Carole Barnes and Benjamin A. Raby and Fernando D. Martinez and Frank D Gilliland and L. Keoki Williams and Esteban Gonz{\`a}lez Burchard and Scott T. Weiss and Dan L. Nicolae and Carole Ober},
  journal={The Journal of allergy and clinical immunology},
  volume={130 6},
BACKGROUND Genome-wide association studies of asthma have implicated many genetic risk factors, with well-replicated associations at approximately 10 loci that account for only a small proportion of the genetic risk. OBJECTIVES We aimed to identify additional asthma risk loci by performing an extensive replication study of the results from the EVE Consortium meta-analysis. METHODS We selected 3186 single nucleotide polymorphisms for replication based on the P values from the EVE Consortium… CONTINUE READING
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