Further evidence of a target organ defect in the syndrome of testicular feminization.

  title={Further evidence of a target organ defect in the syndrome of testicular feminization.},
  author={F. French and J. V. Van Wyk and B. Baggett and W. Easterling and L. Talbert and F. Johnston and E. Forchielli and A. C. Dey},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={26 5},
Two patients with the syndrome of testicular feminization had peripheral venous plasma and urinary testosterone levels similar to those of normal adult males. In one, testosterone was 38.5 μg/100 ml in gonadal venous plasma. The disappearance rates of testosterone-4-14C in plasma of both patients were like those of normal adult male and female controls. Urinary metabolites of labeled testosterone likewise did not differ from those of normals. Plasma estradiol was in the range for normal adult… Expand
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