Further evidence for a third deafness gene within the DFNA2 locus.

DFNA2 is a complex locus. Two hearing loss genes have been identified at this site: GJB3, the gene that encodes the gap junction protein connexin 31, and KCNQ4, a voltage-gated potassium channel gene. A third gene has previously been postulated to explain the hearing loss in an Indonesian family linked to the region but devoid of mutation in either known… CONTINUE READING