Further evidence for a physiological role for hypothalamic dopamine in thermoregulation in the rat.

@article{Cox1980FurtherEF,
  title={Further evidence for a physiological role for hypothalamic dopamine in thermoregulation in the rat.},
  author={Barry Cox and Tony Jer-Fu Lee},
  journal={The Journal of physiology},
  year={1980},
  volume={300},
  pages={7-17}
}
1. Intrahypothalamic injection of either dopamine or noradrenaline in a dose volume of 1 mul. caused a fall in core temperature in lightly restrained rats maintained at an ambient temperature of 17 +/- 1 degrees C.2. The hypothermic effects of dopamine (10 mug) and noradrenaline (2 mug) were selectively antagonized by systemic pre-treatment with pimozide (0.5 mg/kg) and phentolamine (1 mg/kg) respectively.3. The location of the dopamine- and noradrenaline-sensitive sites were defined more… CONTINUE READING

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