Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor.

@article{Marighetto2000FurtherEF,
  title={Further evidence for a dissociation between different forms of mnemonic expressions in a mouse model of age-related cognitive decline: effects of tacrine and S 17092, a novel prolyl endopeptidase inhibitor.},
  author={Aline Marighetto and Khalid Touzani and Nicole Etchamendy and C C Torrea and Guillaume De Nanteuil and David Guez and Robert Jaffard and Philippe Morain},
  journal={Learning & memory},
  year={2000},
  volume={7 3},
  pages={159-69}
}
It has been demonstrated previously on the radial maze that the emergence of an age-related mnemonic impairment is critically dependent on the form which the discrimination problems took. Hence, when the arms were presented one by one (i.e., successive go-no-go discrimination), both adult and aged mice learned to distinguish between positive (baited) and negative (unbaited) arms readily, as evidenced by their increased readiness to enter positive relative to negative arms (i.e., by a… CONTINUE READING