Corpus ID: 33697635

Further evaluation of the discriminative effects of morphine in the rat.

@article{Shannon1977FurtherEO,
  title={Further evaluation of the discriminative effects of morphine in the rat.},
  author={H. Shannon and S. G. Holtzman},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1977},
  volume={201 1},
  pages={
          55-66
        }
}
  • H. Shannon, S. G. Holtzman
  • Published 1977
  • Medicine
  • The Journal of pharmacology and experimental therapeutics
  • Rats were trained in a two-choice discrete trial avoidance paradigm to discriminate between saline and 3.0 mg/kg of morphine. Behavior was considered to be under stimulus ocntrol when the rats completed at least 90% of the trials in a 20-trial session on the morphine-appropriate choice lever after receiving morphine and when they completed at least 90% of the trials on the saline-appropriate choice lever after receiving saline. The discriminative effects of morphine, measured by responding on… CONTINUE READING
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