Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol.

@article{Osullivan2005FurtherCO,
  title={Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol.},
  author={Saoirse E O'sullivan and David Arthur Kendall and Michael D Randall},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2005},
  volume={317 1},
  pages={
          428-38
        }
}
We have previously shown that over time (2 h), the active ingredient of cannabis, Delta(9)-tetrahydrocannabinol (THC), produces peroxisome proliferator-activated receptor (PPAR) gamma-mediated vasorelaxation of conduit arteries. We have now investigated whether incubation with THC affects agonist-stimulated contractile (methoxamine) and endothelium-dependent vasorelaxant (acetylcholine) responses in the rat superior mesenteric artery (G0) and aorta by myography. We have also investigated… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

Similar Papers

Loading similar papers…