Further analysis of the effects of cholecystokinin octapeptides on avoidance behaviour in rats.

@article{Fekete1984FurtherAO,
  title={Further analysis of the effects of cholecystokinin octapeptides on avoidance behaviour in rats.},
  author={M. A. R. De Fekete and Anna Lengyel and B Heged{\"u}s and Botond Penke and M Zar{\'a}ndy and Gabor X Toth and Gyula Telegdy},
  journal={European journal of pharmacology},
  year={1984},
  volume={98 1},
  pages={79-91}
}
Experiments were performed to examine the acute effects of cholecystokinin octapeptides and fragments on the active and passive avoidance behaviour of rats following peripheral and central administration. Both the sulphated (CCK-8-SE) and non-sulphated cholecystokinin octapeptide (CCK-8-NS) and also the COOH-terminal tetra-, penta-, hexa- and heptapeptides of cholecystokinin octapeptide facilitated the extinction of active avoidance behaviour and retention of passive avoidance behaviour. This… CONTINUE READING