Further Evidence for Aberrant Prefrontal Salience Coding in Schizophrenia

  title={Further Evidence for Aberrant Prefrontal Salience Coding in Schizophrenia},
  author={Henrik Walter and Stephan Heckers and Jan Kassubek and Susanne Erk and Karel Frasch and Birgit Abler},
  booktitle={Front. Behav. Neurosci.},
The revised dopamine hypothesis of schizophrenia postulates that dopamine metabolism is impacted differently with increased dopamine in the subcortical mesolimbic system and decreased dopamine in prefrontal cortical regions. Recently, we described findings supporting this hypothesis using a financial reward task in patients with schizophrenia (Walter et al., 2009). In addition to analysing prediction and prediction error coding, we found in this study evidence for aberrant cortical… CONTINUE READING
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