Further Attempts to Analyse the Roles of Epidermis and Deeper Tissues in Experimental Chemical Carcinogenesis by Transplantation and Other Methods

WHEN a carcinogenic agent is applied to the skin of a mouse epithelial hyper-plasia follows in the course of a week or two. If the applications are then stopped, the epidermis reverts to a histologically normal appearance, but if hyperplasia is again induced by the co-carcinogen croton oil, tumours of the skin will in due course be elicited. It is clear… CONTINUE READING