Furosemide ototoxicity: clinical and experimental aspects.

@article{Rybak1985FurosemideOC,
  title={Furosemide ototoxicity: clinical and experimental aspects.},
  author={Leonard P Rybak},
  journal={The Laryngoscope},
  year={1985},
  volume={95 9 Pt 2 Suppl 38},
  pages={1-14}
}
Furosemide is an ototoxic diuretic. Furosemide injection is followed by a rapid, but reversible decrease of the endocochlear potential and eighth nerve action potential with a more gradual decrease of the endolymph potassium concentration. In contrast to the reversible effects of furosemide alone on the cochlea, the combination of kanamycin with furosemide resulted in irreversible changes in cochlear function which were associated with elevated levels of kanamycin in the blood and perilymph of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Pharmacodynamics of intravenous frusemide bolus in critically ill patients.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine • 2017

Prevalence of Auditory Problems in Children With Feeding and Swallowing Disorders.

Journal of speech, language, and hearing research : JSLHR • 2017
View 1 Excerpt

A review of diuretic use in dialysis patients.

Advances in peritoneal dialysis. Conference on Peritoneal Dialysis • 2014

Similar Papers

Loading similar papers…