Furfural inhibits growth by limiting sulfur assimilation in ethanologenic Escherichia coli strain LY180.

  title={Furfural inhibits growth by limiting sulfur assimilation in ethanologenic Escherichia coli strain LY180.},
  author={Elliot Miller and Laura R. Jarboe and Peter C. Turner and Priti Pharkya and Lorraine P. Yomano and Sean W. York and David S. Nunn and Keelnatham T Shanmugam and Lonnie O'Neal Ingram},
  journal={Applied and environmental microbiology},
  volume={75 19},
A wide variety of commercial products can be potentially made from monomeric sugars produced by the dilute acid hydrolysis of lignocellulosic biomass. However, this process is accompanied by side products such as furfural that hinder microbial growth and fermentation. To investigate the mechanism of furfural inhibition, mRNA microarrays of an ethanologenic strain of Escherichia coli (LY180) were compared immediately prior to and 15 min after a moderate furfural challenge. Expression of genes… CONTINUE READING
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