Furanone at subinhibitory concentrations enhances staphylococcal biofilm formation by luxS repression.

Abstract

Brominated furanones from marine algae inhibit multicellular behaviors of gram-negative bacteria such as biofilm formation and quorum sensing (QS) without affecting their growth. The interaction of furanone with QS in gram-positive bacteria is unknown. Staphylococci have two QS systems, agr and luxS, which lower biofilm formation by two different pathways… (More)
DOI: 10.1128/AAC.01704-08

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