Fungicidal properties of two saponins from Capsicum frutescens and the relationship of structure and fungicidal activity.

@article{DeLucca2006FungicidalPO,
  title={Fungicidal properties of two saponins from Capsicum frutescens and the relationship of structure and fungicidal activity.},
  author={Anthony J. De Lucca and Stephen M. Boue and Muriel S. Palmgren and Klaus Maskos and Thomas E. Cleveland},
  journal={Canadian journal of microbiology},
  year={2006},
  volume={52 4},
  pages={
          336-42
        }
}
Two steroidal saponins have been purified from cayenne pepper (Capsicum frutescens). Both have the same steroidal moiety but differ in the number of glucose moieties: the first saponin has four glucose moieties (molecular mass 1081 Da) and the second contains three glucose moieties (molecular mass 919 Da). Solubility in aqueous solution is less for the saponin containing three glucose moieties than for the one containing four glucose moieties. The larger saponin was slightly fungicidal against… 
View on PubMed
doi.org
42 Citations
Highly Influential Citations
2
Background Citations
16
Methods Citations
2

Figures and Tables from this paper

42 Citations

Antifungal Protein from Passion Fruit (Passiflora edulis) Seeds

Antifungal efficacy of Capsicum frutescens L. extracts against some prevalent fungal strains associated with groundnut storage.

The present results suggest that groundnuts treated with C. frutescens fruit extracts are capable of preventing fungal infection to a certain extent.

In vitro activity of CAY-1, a saponin from Capsicum frutescens, against Microsporum and Trichophyton species.

In vitro antifungal activity of CAY-1 against non-germinating conidia and hyphae of clinical isolates of the dermatophytes Trichophyton mentagrophytes, T. tonsurans and Microsporum canis indicates that Cay-1 merits further investigation as a potential agent for the treatment of dermatomycoses.

Antifungal Activity of Capsicum frutescens and Allium cepa against Aspergillus spp . : An Application of Scientific Process Skills by High School Students

High school biology students investigated whether Allium cepa and Capsicum frutescens extracts are effective antifungal agents against Aspergillus niger and A. flavus to practice scientific process skills and serve as a model for students to learn the scientific method practically and to experience different process skills essential in biological research tangibly.

Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids

Pepper is the most widely used spice in the world and is highly valued due to its pungency and unique flavor and possesses antimicrobial, antiseptic, anticancer, counterirritant, appetite stimulator, antioxidant, and immunomodulator activities.

The in Vitro Antifungal Activity of some Nigeria Medicinal Plants against Cryptococcus gattii

The rise in resistance to the few available antifungals has led to increased serach for more antifungals from plant sources. In this study, the leaves of Swietenia mahogani, Senna siamea, Cassia…

Evaluation of CAY-1, an Experimental, Natural Fungicide, for Control of Strawberry Pathogens

CAY-1 strongly reduced the growth of these fungal pathogens in laboratory assays and prevented anthracnose development in detached leaf assays, but it did not control foliar or fruit rot diseases of strawberry in field trials.

Pharmacognostical investigation and standardization of capsicum annum l. Roots

Screening of all extracts indicated the presence of all constituents, and TLC fingerprinting of different extract were also developed which showed a number of bands.

Toxic Chemical Compounds of the Solanaceae

The Solanaceae is comprised of some 2500 species of cosmopolitan plants, especially native to the American continent, which have great value as food, and medicines, like species of Atropa, Withania and Physalis, but many plants of this family are toxic, and sometimes lethal to mammals, in particular to man.

Antifungal activity of Lactococcus lactis against anthracnose pathogen, Colletotrichum capsici of chilli

Anthracnose, caused by Colletotrichum capsici , has impeded output in major chilli-growing regions, resulting in yield losses of 10 to 25%. Our previous In vitro study demonstrated that Lactic acid…

References

SHOWING 1-10 OF 27 REFERENCES

CAY-1, a novel antifungal compound from cayenne pepper.

CAY-1 appears to act by disrupting the membrane integrity of fungal cells, and was active against 16 different fungal strains, including Candida spp.

The chemistry and biological significance of saponins in foods and feedingstuffs.

Methods currently used for the quantitative analysis of saponins, sapogenols, and glycoalkaloids are critically considered; advances in the use of newer methods being emphasized.

Isolation and Structure of Antimicrobial Substances from Paprika Seeds

Antimicrobial substances were isolated from the 50% ethanol extract of paprika seeds by ODS open column chromatography and reverse phase HPLC. Ten compounds (1-10) which demonstrated antimicrobial…

New Acylic Diterpene Glycosides, Capsianosides VI, G and H from the Leaves and Stems of Capsicum annuum L.

Capsicum species are very important plants used as vegetable foods, species and external medicines. In the preceding paper, we disclosed the occurrence of novel acylic diterpene glycosides from…

Steroidal glycosides from Capsicum annuum.

Compromised disease resistance in saponin-deficient plants.

This work isolates saponin-deficient (sad) mutants of a diploid oat species, Avena strigosa, and a number of lines of evidence suggest that this compromised disease resistance is a direct consequence of sap onin deficiency.

Preformed Antimicrobial Compounds and Plant Defense against Fungal Attack.

A complementary approach involving the study of fungal mechanisms of resistance to preformed inhibitors, and of the contribution of this resistance to fungal pathogenicity to the relevant host plants, offers another route toward investigating the importance of these inhibitors in plant defense.

Pathogenicity of ‘take-all’ fungus to oats: Its relationship to the concentration and detoxification of the four avenacins

Steroidsaponine mit mehr als einer Zuckerkette, X. Capsicosid, ein bisdesmosidisches 22‐Hydroxyfurostanol‐Glycosid aus dem Samen von Capsicum annuum L.

Aus dem Samen des Gewurzpaprikas (Capsicum annuum L.) wurde als Hauptglycosid das bisdesmosidische Furostanol-Glycosid Capsicosid (2a) isoliert. Enzymatische Spaltung von 2a fuhrte unter Abspaltung…

Preformed Substances as Potential Protectants

Plant resistance to pathogens based on preformed inhibitory substances is easy to conceive, but despite extensive studies, reviewed by Walker and Stahmann (1955), Allen (1959), Farkas and Kiraly…