Fungicidal properties of two saponins from Capsicum frutescens and the relationship of structure and fungicidal activity.

@article{DeLucca2006FungicidalPO,
  title={Fungicidal properties of two saponins from Capsicum frutescens and the relationship of structure and fungicidal activity.},
  author={Anthony J. De Lucca and Stephen M. Boue and Muriel S. Palmgren and Klaus Maskos and Thomas E. Cleveland},
  journal={Canadian journal of microbiology},
  year={2006},
  volume={52 4},
  pages={
          336-42
        }
}
Two steroidal saponins have been purified from cayenne pepper (Capsicum frutescens). Both have the same steroidal moiety but differ in the number of glucose moieties: the first saponin has four glucose moieties (molecular mass 1081 Da) and the second contains three glucose moieties (molecular mass 919 Da). Solubility in aqueous solution is less for the saponin containing three glucose moieties than for the one containing four glucose moieties. The larger saponin was slightly fungicidal against… 

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References

SHOWING 1-10 OF 27 REFERENCES

CAY-1, a novel antifungal compound from cayenne pepper.

CAY-1 appears to act by disrupting the membrane integrity of fungal cells, and was active against 16 different fungal strains, including Candida spp.

The chemistry and biological significance of saponins in foods and feedingstuffs.

Methods currently used for the quantitative analysis of saponins, sapogenols, and glycoalkaloids are critically considered; advances in the use of newer methods being emphasized.

Isolation and Structure of Antimicrobial Substances from Paprika Seeds

Antimicrobial substances were isolated from the 50% ethanol extract of paprika seeds by ODS open column chromatography and reverse phase HPLC. Ten compounds (1-10) which demonstrated antimicrobial

New Acylic Diterpene Glycosides, Capsianosides VI, G and H from the Leaves and Stems of Capsicum annuum L.

Capsicum species are very important plants used as vegetable foods, species and external medicines. In the preceding paper, we disclosed the occurrence of novel acylic diterpene glycosides from

Steroidal glycosides from Capsicum annuum.

Compromised disease resistance in saponin-deficient plants.

This work isolates saponin-deficient (sad) mutants of a diploid oat species, Avena strigosa, and a number of lines of evidence suggest that this compromised disease resistance is a direct consequence of sap onin deficiency.

Preformed Antimicrobial Compounds and Plant Defense against Fungal Attack.

A complementary approach involving the study of fungal mechanisms of resistance to preformed inhibitors, and of the contribution of this resistance to fungal pathogenicity to the relevant host plants, offers another route toward investigating the importance of these inhibitors in plant defense.

Steroidsaponine mit mehr als einer Zuckerkette, X. Capsicosid, ein bisdesmosidisches 22‐Hydroxyfurostanol‐Glycosid aus dem Samen von Capsicum annuum L.

Aus dem Samen des Gewurzpaprikas (Capsicum annuum L.) wurde als Hauptglycosid das bisdesmosidische Furostanol-Glycosid Capsicosid (2a) isoliert. Enzymatische Spaltung von 2a fuhrte unter Abspaltung

Preformed Substances as Potential Protectants

Plant resistance to pathogens based on preformed inhibitory substances is easy to conceive, but despite extensive studies, reviewed by Walker and Stahmann (1955), Allen (1959), Farkas and Kiraly