Fungicidal effect of isoquercitrin via inducing membrane disturbance.

  title={Fungicidal effect of isoquercitrin via inducing membrane disturbance.},
  author={Jieun Yun and Hee-Jung Lee and Hae Ju Ko and E R Woo and Dong Gun Lee},
  journal={Biochimica et biophysica acta},
  volume={1848 2},
Isoquercitrin is a flavonoid isolated from Aster yomena, which has been used as a traditional medicinal herb. In the present study, we investigated the antifungal activity and the underlying mechanism of isoquercitrin. Isoquercitrin had a potent effect in the susceptibility test against pathogenic fungi and almost no hemolysis. Propidium iodide and potassium release assays were conducted in Candida albicans, and these studies confirmed that isoquercitrin induced membrane damage, thereby… CONTINUE READING
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