Fungicidal effect of antimicrobial peptide arenicin-1.

  title={Fungicidal effect of antimicrobial peptide arenicin-1.},
  author={Cana Park and Dong Gun Lee},
  journal={Biochimica et biophysica acta},
  volume={1788 9},
Arenicin-1 is a 21-residue peptide which was derived from Arenicola marina. In this study, we investigated the antifungal effects and its mechanism of action towards human pathogenic fungi. Arenicin-1 exerted remarkable fungicidal activity with both energy-dependent and salt-insensitive manners. To investigate the fungicidal mechanisms of arenicin-1, the membrane interactions of arenicin-1 were examined. Flow cytometric analysis, using propidium iodide (PI) and bis-(1,3-dibutylbarbituric acid… CONTINUE READING

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