Fungi, dendritic cells and receptors: a host perspective of fungal virulence.

@article{Romani2002FungiDC,
  title={Fungi, dendritic cells and receptors: a host perspective of fungal virulence.},
  author={Luigina Romani and Francesco Bistoni and Paolo Puccetti},
  journal={Trends in microbiology},
  year={2002},
  volume={10 11},
  pages={508-14}
}
An association between morphogenesis and virulence has long been presumed for dimorphic fungi that are pathogenic to humans, as one morphotype exists in the environment or during commensalism, and another within the host during the disease process. For Candida albicans, putative virulence factors include the ability to switch between saprophytic yeast and pathogenic, filamentous forms of the fungus. Dendritic cells sense either form in a specific way, resulting in distinct, T-helper-cell… CONTINUE READING

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