Fungal secondary metabolism — from biochemistry to genomics
@article{Keller2005FungalSM, title={Fungal secondary metabolism — from biochemistry to genomics}, author={Nancy P. Keller and Geoffrey Turner and Joan W Bennett}, journal={Nature Reviews Microbiology}, year={2005}, volume={3}, pages={937-947} }
Much of natural product chemistry concerns a group of compounds known as secondary metabolites. These low-molecular-weight metabolites often have potent physiological activities. Digitalis, morphine and quinine are plant secondary metabolites, whereas penicillin, cephalosporin, ergotrate and the statins are equally well known fungal secondary metabolites. Although chemically diverse, all secondary metabolites are produced by a few common biosynthetic pathways, often in conjunction with…
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