Fungal adhesion protein guides community behaviors and autoinduction in a paracrine manner.

@article{Wang2013FungalAP,
  title={Fungal adhesion protein guides community behaviors and autoinduction in a paracrine manner.},
  author={Linqi Wang and Xiuyun Tian and Rachana Gyawali and Xiaorong Lin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 28},
  pages={11571-6}
}
Microbes live mostly in a social community rather than in a planktonic state. Such communities have complex spatiotemporal patterns that require intercellular communication to coordinate gene expression. Here, we demonstrate that Cryptococcus neoformans, a model eukaryotic pathogen, responds to an extracellular signal in constructing its colony morphology. The signal that directs this community behavior is not a molecule of low molecular weight like pheromones or quorum-sensing molecules but a… CONTINUE READING