Fungal Recognition by TLR2 and Dectin-1.

  title={Fungal Recognition by TLR2 and Dectin-1.},
  author={Helen S. Goodridge and David M Underhill},
  journal={Handbook of experimental pharmacology},
The innate immune system utilizes multiple receptors to recognize fungal pathogens, and the net inflammatory response is controlled by interactions between these receptors. Many fungi are recognized, at least in part, by Toll-like receptor 2 (TLR2) and Dectin-1. Examination of the roles these receptors play together and on their own is a useful model for understanding the interplay between innate immune receptors. This review focuses on the role(s) of TLR2 and Dectin-1 in triggering… CONTINUE READING
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