Fundamentals of planarian regeneration.

@article{Reddien2004FundamentalsOP,
  title={Fundamentals of planarian regeneration.},
  author={Peter W Reddien and Alejandro S{\'a}nchez Alvarado},
  journal={Annual review of cell and developmental biology},
  year={2004},
  volume={20},
  pages={
          725-57
        }
}
The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and proportion (morphallaxis). Because blastemas do not replace all tissues following most types of injuries, both blastema formation and morphallaxis are needed… CONTINUE READING
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