Fundamental structure-activity relationships associated with a new structural class of respiratory syncytial virus inhibitor.

@article{Yu2003FundamentalSR,
  title={Fundamental structure-activity relationships associated with a new structural class of respiratory syncytial virus inhibitor.},
  author={Kuo Long Yu and Yi Zhang and Rita L. Civiello and Kathleen F. Kadow and Christopher M. Cianci and Mark R Krystal and Nicholas A Meanwell},
  journal={Bioorganic & medicinal chemistry letters},
  year={2003},
  volume={13 13},
  pages={
          2141-4
        }
}
Structure-activity relationships surrounding the dialkylamino side chain of a series of benzotriazole-derived inhibitors of respiratory syncytial virus fusion based on the screening lead 1a were examined. The results indicate that the topology of the side chain is important but the terminus element offers considerable latitude to modulate physical properties. 

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