Fundamental of Secondary Structures in Peptide Based Synthetic Nanovaccine Development

Abstract

The peptides vaccines are composed of the twenty genetically coded amino acids generally exist as an ensemble of different conformational states in solution. The induction of folded conformations in short peptide vaccine sequences may be achieved by the incorporation of stereochemically constrained non-coded amino acids. The aim of this review briefly provides basic understanding of method of vaccine development. Copyright: © 2016 Appavu R, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Extracted Key Phrases

2 Figures and Tables

Showing 1-10 of 18 references

Fundamental of Secondary Structures in Peptide Based Synthetic Nanovaccine Development

  • R Appavu, D Mohan, R Kakumanu, G Munisamy
  • 2016

Enhancing the Magnitude of Antibody Responses through Biomaterial Stereochemistry

  • A Rajagoapl, Bc Charles, Alexeyyk, Ds Joshua, Jk Frederick
  • 2015

Self-Assembly of Heterochiral Peptides with Varied Sequence Patterns

  • Alexey Koyfman, Y Appavu, R Sheller, S Rudra, Js
  • 2015

Interruption of a 3(10)-helix by a single Gly residue in a poly-Aib motif: a crystallographic study

  • Helliwell Solà, J Clayden, Mj
  • 2011