Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

@article{Bouton2001FunctionsOT,
  title={Functions of the adapter protein Cas: signal convergence and the determination of cellular responses},
  author={Amy H. Bouton and Rebecca B. Riggins and Pamela J Bruce-Staskal},
  journal={Oncogene},
  year={2001},
  volume={20},
  pages={6448-6458}
}
Since Cas was first identified as a highly phosphorylated 130 kilodalton protein that associated with the v-Src and v-Crk-oncoproteins, considerable effort has been made to determine its function. Its predicted role as a scaffolding molecule based on its domain structure has been largely confirmed. Through its ability to undergo rapid changes in phosphorylation, subcellular localization and association with heterologous proteins, Cas may spatially and temporally regulate the function of its… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 74 extracted citations

p130CAS is required for netrin signaling and commissural axon guidance.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2007
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Cel

S Kook, SR Shim, +4 authors WK. Song
Biochem. Funct., 18, 1 ± 7. • 2000
View 4 Excerpts
Highly Influenced

Cell

CL Weidow, DS Black, JB Bliska, AH. Bouton
Microbiol., 2, 549 ± 560. • 2000
View 5 Excerpts
Highly Influenced

Meth

Z. Songyang
Enzymol., 332, 171 ± 183. • 2001
View 1 Excerpt

Biochim

MT Harte, M Macklem, CL Weidow, JT Parsons, AH. Bouton
Biophys. Acta, 1499, 34 ± 48. • 2000
View 3 Excerpts

Microb

RR Isberg, Z Hamburger, P. Dersch
Infect., 2, 793 ± 801. • 2000
View 2 Excerpts

Mol

L Xing, C Ge, +3 authors K. Alexandropoulos
Cell. Biol., 20, 7363 ± 7377. • 2000

Trends Cell

GM O'Neill, SJ Fashena, EA. Golemis
Biol., 10, 111 ± 119. • 2000

Am

T Takahashi, Y Kawahara, T Taniguchi, M. Yokoyama
J. Physiol. - Heart Circul. Physiol., 43, H1059 ±H1065. • 1998

Biochem

A Sorokin, E. Reed
J., 334, 595 ± 600. • 1998

Gene

E Kiyokawa, Y Hashimoto, +3 authors M. Matsuda
Dev., 12, 3331 ± 3336. • 1998
View 1 Excerpt

Similar Papers

Loading similar papers…