Functions of the Signal Transducer and Activator of Transcription 6 in a Behavioral Animal Model of Depression.

AIMS Depression is one of the most common inflammatory and mental disorders. Signal transducer and activator of transcription 6 (STAT6) plays a crucial role in the pathology of mental disorders as well as inflammatory diseases. METHODS Here we determined the role of STAT6 in the pathogenesis of depression using STAT6-deficient mice in a forced swimming… (More)