Functions of the HIV-1 matrix protein p17.

  title={Functions of the HIV-1 matrix protein p17.},
  author={Simona Fiorentini and Elena Marini and Sonia Caracciolo and Arnaldo Caruso},
  journal={The new microbiologica},
  volume={29 1},
HIV-1 replication is a dynamic process influenced by a combination of viral and host factors. The HIV-1 matrix protein p17 is a structural protein critically involved in most stages of the life cycle of the retrovirus. It participates in the early stages of virus replication as well as in RNA targeting to the plasma membrane, incorporation of the envelope into virions and particle assembly. Besides its well established functions, p17 acts as a viral cytokine that works on preactivated--but not… CONTINUE READING