Functions of the Drosophila JAK-STAT pathway

@inproceedings{Amoyel2012FunctionsOT,
  title={Functions of the Drosophila JAK-STAT pathway},
  author={Marc Amoyel and Erika A Bach},
  booktitle={JAK-STAT},
  year={2012}
}
JAK-STAT signaling has been proposed to act in numerous stem cells in a variety of organisms. Here we provide an overview of its roles in three well characterized stem cell populations in Drosophila, in the intestine, lymph gland and testis. In flies, there is a single JAK and a single STAT, which has made the genetic dissection of pathway function considerably easier and facilitated the analysis of communication between stem cells, their niches and offspring. Studies in flies have revealed… CONTINUE READING

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