Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis

@inproceedings{Zhu2009FunctionsOT,
  title={Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis},
  author={Lei Zhu and Juanli Cheng and Biao Luo and Saixiang Feng and Jinshui Lin and Shengbin Wang and John E. Cronan and Haihong Wang},
  booktitle={BMC Microbiology},
  year={2009}
}
The original anaerobic unsaturated fatty acid biosynthesis pathway proposed by Goldfine and Bloch was based on in vivo labeling studies in Clostridium butyricum ATCC 6015 (now C. beijerinckii) but to date no dedicated unsaturated fatty acid biosynthetic enzyme has been identified in Clostridia. C. acetobutylicium synthesizes the same species of unsaturated fatty acids as E. coli, but lacks all of the known unsaturated fatty acid synthetic genes identified in E. coli and other bacteria. A… CONTINUE READING