Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.

@article{Knauth2005FunctionsOS,
  title={Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking.},
  author={Peter Knauth and Thomas Schl{\"u}ter and Martin Czubayko and Cornelia Kirsch and Volker Florian and Susan Schreckenberger and Heidi Ann Hahn and Ralf Bohnensack},
  journal={Journal of molecular biology},
  year={2005},
  volume={347 4},
  pages={813-25}
}
SNX17 is a member of the sorting nexin family (SNX), a group of hydrophilic proteins whose common characteristic property is a phox homology (PX) domain. The PX domain directs SNXs to phosphatidylinositides containing membranes of the endosomal compartment, where the SNXs are involved in the sorting of transmembrane proteins. SNX17 is known to interact with P-selectin and the LDL receptor family. Here, we report that the PX domain of SNX17 specifically binds to phosphatidylinositol 3-phosphate… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…