Functions of peripheral 5-hydroxytryptamine receptors, especially 5-hydroxytryptamine4 receptor, in gastrointestinal motility

@article{Taniyama2000FunctionsOP,
  title={Functions of peripheral 5-hydroxytryptamine receptors, especially 5-hydroxytryptamine4 receptor, in gastrointestinal motility},
  author={Kohtaro Taniyama and Noriaki Makimoto and Akira Furuichi and Yasuko Sakurai-Yamashita and Yoshihisa Nagase and M. K. Kaibara and Takashi Kanematsu},
  journal={Journal of Gastroenterology},
  year={2000},
  volume={35},
  pages={575-582}
}
The multiple 5-hydroxytryptamine (5-HT, serotonin) receptor subtypes are distinguished. In this article, we described mainly the 5-HT4 receptor of four subtypes of functional 5-HT receptors, 5-HT1, 5-HT2, 5-HT3, and 5-HT4, recognized in the gastrointestinal tract. In-vivo microdialysis experiments determined that activation of the 5-HT4 receptor stimulated intestinal motor activity associated with a local increase in acetylcholine (ACh) release from the intestinal cholinergic neurons in the… CONTINUE READING
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Regional difference in correlation of 5-HT4 receptor distribution with cholinergic transmission in the guinea pig stomach

  • K Takada, Y S-Yamashita, K Yamashita, M Kaibara, Y Hamada, Y Nakane
  • Eur J Pharmacol
  • 1999

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