Functions of neuronal P2Y receptors

  title={Functions of neuronal P2Y receptors},
  author={Simon Hussl and Stefan Boehm},
  journal={Pfl{\"u}gers Archiv},
Within the last 15 years, at least eight different G protein-coupled nucleotide receptors, i.e., P2Y receptors, have been characterized by molecular means. While ionotropic P2X receptors are mainly involved in fast synaptic neurotransmission, P2Y receptors rather mediate slower neuromodulatory effects. This P2Y receptor-dependent neuromodulation relies on changes in synaptic transmission via either pre- or postsynaptic sites of action. At both sites, the regulation of voltage-gated or… CONTINUE READING


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